产品货号：
Z24221
中文名称：
Podoplanin/PDPN抗体
英文名称：
Anti-Podoplanin/PDPN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Podoplanin/PDPN Antibody |
| 指标别名 | AGGRUS;D2 40;D2 40;M2A;Glycoprotein 36;GP36;Gp38;GP40;HT1A 1;M2A;OTS8;PA2.26;PA2.26 antigen;PDPN;podoplanin;PSEC0025;T1 alpha;T1A;T1A 2 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB |
| 基因名称 | PDPN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of rat Podoplanin/gp36(155-166aa VVMRKISGRFSP),different from the related mouse sequence by one amino acid. |
| 实际分子量 | 38KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PDPN(Podoplanin),also called T1A,T1A2,GP36,OTS8 or AGGRUS,is a protein that in humans is encoded by the PDPN gene.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues.The PDPN gene is mapped to chromosome 1 by the International radiation Hybrid mapping consortium.The physiological function of PDPN may be related to its mucin-type character.The specific function of this protein has not been determined but it has been proposed as a marker of lung injury.Immunohistochemical analysis of PDPN in placenta,kidney,lung,and nasal polyps showed expression at the apical plasma membrane of vascular endothelial cells and in alveolar epithelial cells.Overexpression of rat PDPN in human and rodent endothelial cells promoted formation of elongated cell extensions and significantly increased endothelial cell adhesion,migration,and tube formation.Inhibition of PDPN expression by small interfering RNAs decreased cell adhesion in cultured human dermal lymphatic endothelial cells. |
| Uniprot ID | Q64294 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | podoplanin |
| 蛋白名全称 | Podoplanin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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